Experience Profound Transformation

We are pioneering transformative wellness. Let us be your guide.


Why Synthesis?

Synthesis is a legal, medically supervised, psilocybin retreat center for professionals to experience personal growth, emotional breakthroughs and spiritual development.


Medical Safety

Our team of medical professionals perform comprehensive medical screenings for all applicants in order to identify any personal health risks, ensuring the safety of all of our participants. 


Best Practices

The Synthesis Retreat Team consists of experienced professionals; trained in the best practices used in clinical trials, they have prepared and guided hundreds of participants safely through the full variety of psychedelic experiences.


Scientifically Validated

Through our collaboration with the Psychedelic Research Group at Imperial College London, Synthesis is contributing to pioneering data. Even in healthy individuals, we found a 42.4% sustained reduction in depressive symptoms. 




The Synthesis Experience


What can you expect?

  • Peak experiences

  • Suppressed feelings (both positive & negative)

  • Experiences of intense, all-encompassing love and bliss

  • Remembering meaningful memories

  • Synesthesia

  • Challenging and confronting visions

  • Intellectual epiphanies

  • Self-acceptance and compassion

  • Heightened states of creativity

  • Processing childhood experiences

  • Mystical states

  • Overcoming destructive attachments

  • Deep and lasting sense of connection

*While there are no guarantees as to what kind of journey you will have - these are the most-commonly known types of psychedelic experiences.


  • Individual Health Screening

  • In Depth Exploration Call

  • Group Preparation

  • Private 1:1 Coaching

  • Carefully Curated Set & Setting

  • Embodied Wisdom Practices

  • Ceremonial Psilocybin Experiences

  • Educational Workshops

  • Group Integration

  • Access to Additional Programs

  • Private Inner Circle Membership


The Lighthouse:
A House of Well Being

Located in a quiet seaside village just minutes outside of Amsterdam, The Lighthouse is beautifully hundred year old renovated church. Created with love, it is hard to explain the magic of the space, it really has to be experienced to be appreciated. 

Each guest is welcomed to their private apartment with access to soothing gardens all around the property, plenty of private and communal spaces for you to explore on your journey, and of course, our sauna and private yoga space. 

Our in house chef prepares delicious, healthy vegan meals and caters to any special dietary needs that are guests may have.   




Choose Your Journey

Synthesis offers four distinct all-inclusive retreats:

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Expansion by Synthesis

Our most comprehensive program, Expansion is a complete 9-week program designed for deep transformations. More than just a psilocybin ceremony, you will use this window of plasticity to grow your presence, self-acceptance, focus, and expand your range of states of consciousness in your daily life.

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Core by Synthesis

Our standard 3-day retreat near Amsterdam in which you experience one dose of utilize moderate-to-high doses of psilocybin truffles to catalyze emotional breakthroughs and deepen self-understanding.

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Women’s Leadership Retreat

Leadership is born from the relationship we have with ourselves; it is not a job title, it is a decision. We believe that true leadership is something that all women can access, with the right tools. During this five-day wellness retreat, made by women for women, you will relax, explore, learn, discover, breathe, heal, recharge and reach a state of alignment with your past, present and future selves, and the world around you.

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Private Retreat

Synthesis offers private retreats, an opportunity to work with two facilitators privately instead of participating in our larger group retreat model. The private retreat format offers participants the ability to customize their ceremony, tailoring the individual needs to maximize the transformational potential of their experience. Click below to see if this retreat is right for you.




Here’s what you need to know


Synthesis is a Legal Psilocybin Center

Based in the Netherlands, we offer a 100% legal way to explore your mind with psilocybin. Access to expanded states of consciousness in a modern, comfortable, medically supervised context.

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Medically Supervised

The application procedure involves a thorough health check by our medical team to ensure your safety. We also have medical practitioners present during the retreat. Proper medical supervision is always prioritized by the Synthesis team, providing safety and peace of mind for all retreat participants is a key part of our model.

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Personalised Care

Your journey begins with an in-depth exploration call to fully understand your background and needs, so we can provide absolute clarity in the journey ahead and how to get the most out of your experience. Throughout the retreat, we cater to your individual needs by offering workshops for all levels and one-on-one consultations with our professionals, in order for you to go in prepared and process your experience to extract valuable life lessons.


Preparation & Integration

All our programs include a preparation and integration program. Preparation is key for maximising the potential of a beneficial psychedelic experience and integration is important for prolonging the benefits in well-being. We are dedicated to ensuring that our participants understand the unique ways that psilocybin can aid in healing and growth, the importance of set, setting, intentions, and personal practices.


Set & Setting

We designed your whole journey in order to reduce any anxiety or nervousness you might feel. From the sound experience to personalized care, everything is planned to make you feel most comfortable and be able to approach the psychedelic experience with as little resistance as possible.

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Inner Circle

You will receive lifetime access to our private community as part of your retreat commitment. This will be an ever-evolving group that will provide professional support and networking as you continue the process of your own psychedelic journey and personal development.


Contributing to Science

Synthesis is committed to science-based data and contributing to research. To date we’ve collaborated with The Psychedelic Research Group of Imperial College London in a pilot study where we discovered that the biggest factors for a transformational psychedelic journey are: sense of safety, quality of intention, the absence of escapist behaviours and distractions, and the feeling of community - all important aspects that we safeguard. By attending Synthesis you get the opportunity to contribute to pioneering science and furthering the well-being of our planet.




Upcoming Retreats 



3-Day Retreat

Your facilitators: Natasja Pelgrom (lead facilitator), Tessa Van de Ven (assistant facilitator).


3-Day Retreat

Your facilitators: Natasja Pelgrom (lead facilitator), Adam Rice (co-lead facilitator), Daan Keiman (assistant facilitator).


3-Day Retreat

Your facilitators: Natasja Pelgrom (lead facilitator), Daan Keiman (co-lead facilitator), Alex Pardhy (assistant facilitator).


View more retreat dates:




Featured stories

400+ people have embarked on a journey through Synthesis over the past year. They happily share with you how it has impacted their lives.


“It would be impossible for me to speak too highly of the benefits of undergoing the Synthesis psilocybin retreat. The guidance offered, in the in the weeks leading up to the retreat itself, through the care and commitment of the facilitators before, during and after the ceremony/experience, coupled with the offer of support and assistance, guarantees (to those who ensure they arrive with the right mindset) a successful outcome. I took away from my time in Amsterdam a foundation which I know I can continue to build on in the years to come. My perception of the benefits I've gained have already been confirmed by those near and dear to me and already the benefits have extended beyond the merely personal into my deepest relationships. This has been one of the most truly transformative experiences I've ever undergone. It is without question unlike any of the other modalities I have undertaken over many years and clearly the one that to date has had the most significant impact in enabling me to understand who I am, why I have lived my life as I have to date and what I will now do with what of it remains.”

— Stewart, 62, Insurance, Australia



“The experience has been nothing short of life changing. From the facilitators, to the people I shared the venue with, everyone was warm, caring, and accepting. The Synthesis team is doing amazing work, long may it continue. I can't wait to attend again!”

— William, 37, Recruitment, UK



“I really appreciated the way the Synthesis team was informative, educational and to the point and at the same time sacred and ceremonial. Last but not least I appreciated how they were kept totally secular, that is important to me. What struck me as surprising was that the actual psychedelic journey was a much lesser piece of the overall experience than I had expected. I did expect the surrounding activities to be nice and interesting, but not that they would be essential to the experience and the possibility to learn from it in the way that they turned out to be.”

— Jonah, 40, Teacher, Sweden



“I couldn't think of a better place for a psilocybin retreat. The Synthesis team is very loving and supportive, the building modern and beautiful, the food lovingly prepared. I am glad that I took part and I will come again.”

— Marcel, 53, Teacher, Switzerland



“The Synthesis team is amazing, from the first email to the emotional goodbye hug they are top class every step of the way. Having been to many spiritual/development focused retreats (meditation, motivational speakers, etc) this was one of the most professionally run and knowledgeable I’ve ever been to. Also, as a complete novice to entheogens/psychedelics it was amazing to see how the retreat catered to those of all levels, helping a rookie like me feel very safe & secure while still keeping those with more experience really engaged! Lastly, they do a great job of curating groups of awesome people, while our group was very diverse there was no drama or issues. Amazing experience, people and team!”

— Daniel Figueroa, 27, Market Research & Analytics, Canada



"This retreat allowed me to explore areas in my life I had not been able to easily access. Everyone was professional and lovingly compassionate and caring. A beautiful experience."

— Marion, 66, Psychotherapist, USA



Find out why our participants rate us 9.7/10




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 Please reach out!

We’re committed to making your transformative journey the most meaningful it can be, as well as to educate you with regard to greater self-knowing and the transformative potential of psychedelics. 

Talk to us

Reach our staff by email or schedule a discovery phone call to discuss your personal situation and find out whether Synthesis is the right retreat for you. 

Connect with us

Find us and numerous Synthesis Retreat alumni on LinkedIn, Facebook and Instagram




Frequently Asked Questions


+ How much does it cost?

Our retreat types differ in value, and therefore pricing. Please refer to the retreat pages for more information and price: 3-day Core retreat, 6-day Expansion retreat, 5-day Women’s leadership retreat, 3-day Private Core retreat.

+ Are psilocybin truffles safe?

According to recent studies, psilocybin mushrooms (which have the same active ingredient as truffles) are the safest drug currently available - safer than tobacco, cannabis, and alcohol. These substances are non-addictive, non-toxic, and, when taken within a structured setting, hold little to no risk.

+ Who will facilitate the sessions and what are their qualifications?

Please visit the about page for information on our facilitators and their qualifications. Please feel free to contact us if you have any further questions.

+ How will the psychedelic sessions be set up?

We provide a comfortable indoor space with mattresses to lay down on, eye shades, and profound music. In creating an optimal environment for your psychedelic experience, we combine ceremonial aspects rooted in age-old tradition with modern approaches that have proven, in scientific research, to be effective at facilitating a deep, meaningful experience.

+ Why should I invest in this experience if I can take mushrooms at home?

We believe the context of a group retreat and having experienced guides are essential ingredients to properly optimize for safety and getting the most out of a psychedelic experience. From years of retreat experience we know the value of this experience is rooted in the relationships you will build.

+ Is there any prep or post work included with the retreats?

Prior to the 3-day retreat, you will have a 1-2 hour group video call with your facilitators to discuss the retreat. More preparation documents will be sent over nearing your retreat date. During the retreat, you will have two 30-minute private conversations to discuss anything that might come up. We will always be available for any assistance post-retreat.

+ What is the typical age bracket of people attending retreats at Synthesis?

  • You are over the age of 18
  • You take a mature approach to your work and relationships
  • You are looking for an experience designed to catalyze deeper self-understanding and personal growth
  • You have a developing interest in the safe and responsible use of psychedelics. See more: 'Is Synthesis right for me?'

+ Will my personal information be confidential?

We keep all personal information confidential, none of it will be shared with third parties.

+ Do you offer 1-to-1 guided sessions if I prefer to do this in private?

Yes, we do! Please see our private retreat offer for more details. We also offer 1-to-1 preparation and integration coaching as an option during our group retreats, for an additional fee.

+ Can I do more than one retreat?

Yes, you can. A second retreat can be a quite different experience, certainly not just a repetition. In case it‘s your second overall psychedelic experience, many people tend to be even better prepared and relaxed as there is a familiarity that allows them to let go or direct their experience even more. For experienced psychonauts on the other hand, each experience can have its own focus or topic, exploring different aspects.


Ready to join one of our retreats?